{"id":1094,"date":"2013-04-02T15:59:08","date_gmt":"2013-04-02T19:59:08","guid":{"rendered":"http:\/\/easinc.org\/wordpress\/?p=1094"},"modified":"2014-04-03T13:18:17","modified_gmt":"2014-04-03T17:18:17","slug":"e13-quality-by-design-a-new-paradigm-for-the-analytical-laboratory-ii","status":"publish","type":"page","link":"https:\/\/eas.org\/2024\/e13-quality-by-design-a-new-paradigm-for-the-analytical-laboratory-ii\/","title":{"rendered":"E14 &#8211; Quality-by-Design: A New Paradigm for the Analytical Laboratory II"},"content":{"rendered":"<div>\n<p align=\"center\"><span style=\"font-size: 16px;\"><span style=\"color: #0000ff;\"><b>Quality-by-Design (QbD): A New Paradigm for the Analytical Laboratory II: <br class=\"none\" \/><\/b><\/span><span style=\"color: #0000ff;\"><b>Design of Experiments (DOE) for Analytical Chemists<\/b><\/span><\/span><\/p>\n<\/div>\n<p align=\"center\"><b><i><span style=\"text-decoration: underline;\">One-Day Course<\/span><\/i><\/b><\/p>\n<p align=\"center\">Dr. Zenaida Otero Gephardt, Rowan University, Glassboro, NJ<\/p>\n<p style=\"text-align: justify;\" align=\"center\"><b><span style=\"text-decoration: underline;\">COURSE DESCRIPTION<br class=\"none\" \/><\/span><\/b>Design of Experiments (DOE) is one of the cornerstones of quality-by-design (QbD) in the laboratory. Optimization of experimental design techniques offers the advantage of minimizing the number of experiments required in the laboratory.\u00a0 This improves the efficiency of the laboratory staff and reduces the cost of operation.\u00a0 Experimental design techniques often yield better data, and results that are more meaningful and easier to interpret. Critical quality attributes (CQA) are identified and effects of critical process parameters (CPP) are ascertained and quantified in the most efficient manner.\u00a0 In addition, experimental design allows for optimization of continuous improvement techniques in the laboratory. Many design techniques are simple to use and only require a calculator or spreadsheet software.\u00a0 Experimental design techniques allow laboratory staff to focus on experimental development and to mainstream laboratory operations and regulatory matters.\u00a0 This course will provide participants with analysis tools they can immediately use in their laboratories including an introduction to available experimental design software.\u00a0 Practical applications will be used to illustrate experimental designs throughout the course.<\/p>\n<p style=\"text-align: justify;\" align=\"center\"><b><span style=\"text-decoration: underline;\">WHO SHOULD ATTEND<br class=\"none\" \/><\/span><\/b>Analytical chemists at all levels will benefit from this course.\u00a0 Laboratory supervisors and technical personnel involved in data analysis and reporting will also benefit.<\/p>\n<div>\n<div>\n<p style=\"text-align: left;\" align=\"center\"><span style=\"text-decoration: underline;\"><b>TOPICS<br class=\"none\" \/><\/b><\/span>1. Background and Introduction to QbD Experimental Design Optimization<br class=\"none\" \/>2. Experimental Designs for Simple Linear and Pseudo-Linear Systems\u00a0<br class=\"none\" \/>3. Identifying Key Variables Using Experimental Designs<br class=\"none\" \/>4. Experimental Designs for Initial Stages of Experimental Program: Scouting Designs<br class=\"none\" \/>5. Experimental Designs for Complex Systems<br class=\"none\" \/>6. Experimental Designs for Mixtures<br class=\"none\" \/>7. Continuous Improvement: Evolutionary Experimental Designs<\/p>\n<\/div>\n<\/div>\n<p style=\"text-align: justify;\" align=\"center\"><b><span style=\"text-decoration: underline;\"><a name=\"bio\"><\/a>ABOUT THE INSTRUCTOR<br class=\"none\" \/><\/span><\/b><b>Dr. Zenaida Otero Gephardt<\/b> is Associate Professor of Chemical Engineering at Rowan University (Glassboro, NJ) where she has served as Director of Engineering and Assistant Dean. Dr. Gephardt is also a consultant through Otero Keil Associates.\u00a0 Her research focuses on optimization, development and mathematical modeling of chemical processes and laboratory techniques.\u00a0 She has developed statistical models and experimental designs for a wide range of chemical processes including high pressure, supercritical systems, multi-phase systems and aquaculture applications.\u00a0 Dr. Gephardt has worked with a wide range of system scales ranging from bench scale laboratory systems to large-scale industrial applications.\u00a0 Dr. Gephardt has over 20 years\u2019 experience in analysis and optimization applications in the chemical process industry.\u00a0 She teaches on-site courses for industry and provides analysis and experimental design support.\u00a0 Dr. Gephardt holds a Ph.D. in chemical engineering from the University of Delaware and is a registered Professional Engineer in Delaware.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Quality-by-Design (QbD): A New Paradigm for the Analytical Laboratory II: Design of Experiments (DOE) for Analytical Chemists One-Day Course Dr. Zenaida Otero Gephardt, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1094","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/pages\/1094"}],"collection":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/comments?post=1094"}],"version-history":[{"count":11,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/pages\/1094\/revisions"}],"predecessor-version":[{"id":2466,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/pages\/1094\/revisions\/2466"}],"wp:attachment":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/media?parent=1094"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}