{"id":1114,"date":"2013-04-02T17:18:19","date_gmt":"2013-04-02T21:18:19","guid":{"rendered":"http:\/\/easinc.org\/wordpress\/?p=1114"},"modified":"2013-05-20T16:08:06","modified_gmt":"2013-05-20T20:08:06","slug":"e13-quantitative-lab-skills-for-the-modern-analyst","status":"publish","type":"page","link":"https:\/\/eas.org\/2024\/e13-quantitative-lab-skills-for-the-modern-analyst\/","title":{"rendered":"E13 &#8211; Quantitative Lab Skills for the Modern Analyst"},"content":{"rendered":"<div>\n<p align=\"center\"><span style=\"color: #0000ff; font-size: 16px;\"><b>Quantitative Lab Skills for the Modern Analyst<\/b><b><\/b><\/span><\/p>\n<\/div>\n<p align=\"center\"><b><i><span style=\"text-decoration: underline;\">NEW One-Day Course, E13-18, Monday, November 18th, 8:30am &#8211; 5:00pm<\/span><\/i><\/b><\/p>\n<p style=\"text-align: center;\">\u00a0Dr. Merlin Bicking, ACCTA, Inc., St. Paul, MN<\/p>\n<p style=\"text-align: justify;\" align=\"center\"><b><span style=\"text-decoration: underline;\">COURSE DESCRIPTION\u00a0<br class=\"none\" \/><\/span><\/b>Explanations of the properties of proteins that must be characterized in the course of developing a protein therapeutic drug and monitored during production and lot release begin this class. The theory and practice of a number of chromatographic separation techniques that play key roles in the analysis and characterization of protein therapeutic drugs are then described. The chromatography techniques that are discussed include reversed-phase HPLC, ion exchange, size exclusion and several less well-known techniques in chromatography. Examples of how these are used in the development and release of protein therapeutic drugs are shown.<\/p>\n<p style=\"text-align: justify;\" align=\"center\"><b><span style=\"text-decoration: underline;\">WHO SHOULD ATTEND<br class=\"none\" \/><\/span><\/b>\u00a0This course is designed for new laboratory staff &#8211; either recent graduates or transfers from other non-analytical groups, especially those who have never completed a quantitative analysis course, specialists who want to add new skills or need cross-training instruction, and experienced analysts and technicians who want or need a brief refresher course.\u00a0 Anyone needing the &#8220;education, training, and experience or any combination thereof&#8230;&#8221; to work in a GMP environment.<\/p>\n<div>\n<div>\n<p style=\"text-align: left;\" align=\"center\"><span style=\"text-decoration: underline;\"><b>TOPICS <br class=\"none\" \/><\/b><\/span>1. Mathematical Skills: A Review<b> <br class=\"none\" \/><\/b>\u00a0\u00a0\u00a0\u00a0 * Perspectives<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Units, units conversions and calculations<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Chemical factors<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Significant figures and rounding<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Method-related calculations<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Pegylation and other forms of conjugation <br class=\"none\" \/>2. Using Laboratory Equipment:\u00a0 Avoiding the Most Common Problems<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Analytical Balances<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * pH Meters<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Filtration <br class=\"none\" \/>3. Volumetric Containers:\u00a0 Why We Do What We Do<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * General issues with Volumetric Glassware<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Specifications and calibrations<br class=\"none\" \/>\u00a0\u00a0 \u00a0 * Volumetric flask and pipets<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Pipetting instruments (pipetters)\u00a0 <br class=\"none\" \/>4. Solution Preparation Issues:\u00a0 Putting It All Together<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Propagation of errors<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Preparation of solutions and standards<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Should I choose a parallel or serial dilution scheme<br class=\"none\" \/>\u00a0\u00a0\u00a0\u00a0 * Documentation and observation<\/p>\n<\/div>\n<\/div>\n<p style=\"text-align: justify;\" align=\"center\"><b><span style=\"text-decoration: underline;\"><a name=\"bio\"><\/a>ABOUT THE INSTRUCTOR<br class=\"none\" \/><\/span><\/b><b>Dr. Merlin K. L. Bicking<\/b> is President, <i>ACCTA, Inc.<\/i>\u00a0 He has extensive analytical chemistry experience in academia, contract research, independent testing laboratories, consulting, and technical training.\u00a0 His professional history includes development of two EPA methods, as well as numerous methods in other regulated and non-regulated industries.\u00a0 His publications and presentations cover a wide range of topics, including liquid chromatography theory, derivatization, method optimization, and the use of experimental design strategies in analytical chemistry.\u00a0 He also develops and presents technical training seminars for analytical laboratory staff.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Quantitative Lab Skills for the Modern Analyst NEW One-Day Course, E13-18, Monday, November 18th, 8:30am &#8211; 5:00pm \u00a0Dr. Merlin Bicking, ACCTA, Inc., St. [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"no-title-no-sidebar.php","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1114","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/pages\/1114"}],"collection":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/comments?post=1114"}],"version-history":[{"count":8,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/pages\/1114\/revisions"}],"predecessor-version":[{"id":1463,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/pages\/1114\/revisions\/1463"}],"wp:attachment":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/media?parent=1114"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}