Think Big but Design Small, a Path to Modern Analytical Chemistry
<\/b>Janusz Pawliszyn, University of Waterloo, Department of Chemistry, Waterloo, Ontario, Canada, N2L 3G1<\/p>\n
The presentation summarises my involvement in different areas of Analytical Chemistry leading to miniaturized portable devices and on-side applications.\u00a0 My early work as new faculty in 1980\u2019s on application of technologies developed at that time for communication industry including LEDs, laser diodes, imaging semiconductor arrays and optical fibers are discussed.\u00a0 This work led to construction of different microfluidics devices including whole column imaging detection (WCID) system applied in successful \u201cnow gold standard\u201d analytical CIEF\/WCID instrument widely used in biotech industry for antibody QC and product development.\u00a0\u00a0 The research on optical fibers lead to development of the SPME technology presently used around globe in number of laboratory and on-site applications.\u00a0 Recent developments of new morphologies of extracting materials and novel sampling configurations as well as approaches compatible with high throughput lab and\/or on-site determinations are outlined.\u00a0 The recent development of matrix compatible SPME coating lead to interesting features experienced during extraction, some of them not anticipated.\u00a0 They are not limited to elimination of fouling and saturation effects during direct SPME of complex samples, but also balance coverage property, enabling \u201cvia free form\u201d clean extraction of small molecules widely varying in physical properties leading to some interesting applications.\u00a0 For example, on-site sampling, in-vivo<\/em> metabolomics, and rapid screening via direct coupling of sample preparation to mass spectrometry were facilitated by this development.<\/p>\n To view graphics of two articles that were used by Analytical Chemistry as cover pages visit Anal. Chem. 2017, 89, 8021\u22128026 and 89, 3805\u22123809.<\/p>\n","protected":false},"excerpt":{"rendered":" Think Big but Design Small, a Path to Modern Analytical ChemistryJanusz Pawliszyn, University of Waterloo, Department of Chemistry, Waterloo, Ontario, Canada, N2L 3G1 […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-4865","post","type-post","status-publish","format-standard","hentry","category-info"],"_links":{"self":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/posts\/4865"}],"collection":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/comments?post=4865"}],"version-history":[{"count":1,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/posts\/4865\/revisions"}],"predecessor-version":[{"id":4866,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/posts\/4865\/revisions\/4866"}],"wp:attachment":[{"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/media?parent=4865"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/categories?post=4865"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/eas.org\/2024\/wp-json\/wp\/v2\/tags?post=4865"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}