Dr. Donald Dahlberg, Lebanon Valley College (Emeritus), Annville, PA
Dr. Neal Gallagher, Eigenvector Research, Wenatchee, WA

COURSE DESCRIPTION
Join us for our last presentation of Chemometrics without Equations as we celebrate 20 years of CWE at EAS!  This is a combination of two one-day courses: Introduction to Chemometrics without Equations (Part 1) and Intermediate Chemometrics without Equations (Part 2).  A discount will be offered for the combined course over separately registering for the two one-day courses.  See course descriptions for Introduction to Chemometrics without Equations and Intermediate Chemometrics without Equations.

Part 1: This introductory course concentrates on two areas of chemometrics: (1) exploratory data analysis and pattern recognition, and (2) regression. Participants learn to apply techniques such as Principal Component Analysis (PCA), SIMCA, Principal Component Regression (PCR), and Partial Least Squares regression (PLS) safely. The most commonly used methods of outlier detection and data pretreatment with also be illustrated. The course emphasizes understanding the chemometric process without having to learn matrix algebra.
Part 2: This intermediate course concentrates on two areas of chemometrics: (1) Mixture Analysis and (2) Multivariate Image Analysis. Multivariate Curve Resolution (MCR) is a powerful chemometric technique that allow the user to determine the composition profile and the pure component spectra of mixtures. These techniques can be applied to resolving overlapping peaks in hyphenated chromatography and determining the time or spatial distribution of substances in reactions and heterogeneous mixtures. MCR can be used with time-series data or multivariate/hyperspectral images. Multivariate Image Analysis is the application of chemometric tools to multispectral images used in quality assurance, agriculture, biomedical imaging, surveillance, standoff detection, pharmaceuticals, cultural heritage, forensics and an ever growing number of fields. The course will have hands-on exercises, so that the participants can follow along with the instructor on their own computers.

WHO SHOULD ATTEND
Part 1: This introductory course is designed for those with a desire to explore the problem-solving power of chemometric tools, but are discouraged by the high level of mathematics found in many software manuals and texts. Course emphasis is on proper application and interpretation of chemometric methods as applied to real-life problems. The objective is to teach in the simplest way possible so that participants will be better chemometrics practitioners and managers.

Part 2: This  course is directed toward those who have some experience with the basic tools of chemometrics such as Principal Component Analysis (PCA) and Partial Least Squares (PLS) and want to apply these and other techniques to mixture analysis and/or multispectral images. This course should be of interest to those involved in chromatography and hyperspectral imaging, following changes over time or location, and the analysis of materials in complicated matrices. As with the predecessor course, Chemometrics without Equations, it presents the material without the use of high-level mathematics found in many software manuals and texts. Course emphasis is on proper application and interpretation of chemometric methods as applied to real-life problems. The objective is to teach in the
simplest way possible so that participants will be better chemometrics practitioners and managers.

Dr. Donald Dahlberg (Course Director) is Professor Emeritus of Chemistry at Lebanon Valley College. Dr. Dahlberg earned a B.S. in Chemistry from the University of Washington and a Ph.D. in Physical Chemistry from Cornell University. After decades of doing research in the area of Physical Organic Chemistry, he got involved in Chemometrics while on sabbatical in 1988 at the Center for Process Analytical Chemistry at Washington. There he learned chemometrics in the Bruce Kowalski group (co-founder of chemometrics). Upon returning to LVC, he taught chemometrics to undergraduate students for over a decade. Although retired from the classroom, he continues to do consulting and supervises undergraduate research in industrial chemistry. Dr. Dahlberg wrote and teaches this course so that those not fluent in matrix algebra can take advantage of the powerful tool of chemometrics.

Dr. Neal B. Gallagher, PLS_Toolbox co-author and co-founder of Eigenvector Research, In., holds a doctorate in Chemical Engineering and has experience in a wide variety of applications spanning chemical process monitoring, hyperspectral image analysis, anomaly detection, quantification and classification, regression modeling and analytical instrumental development. He has extensive teaching experience including Eigenvector University and dozens of chemometric courses.