E15-35: Making the Transition to GC-MS, GC-MS-MS and GCxGC-MS

HALF-Day Course
Dr. Nicholas H. Snow, Seton Hall University, South Orange, NJ 
Dr. Gregory C. Slack, Clarkson University, Potsdam, NY

Multidimensional separation and detection are the next “new thing” in gas chromatography.   This course will introduce GC-MS, GC-MS-MS and GCxGC-MS to gas chromatographers that may be considering adding these to their laboratories.  Although GC-MS is not new, many labs are still considering this transition; GCxGC-MS and GC-MS-MS have recently become much more accessible.  In a fast-paced ½ day course, these techniques will be introduced and this costs and benefits discussed.   Participants will gain understanding that will assist in choosing a multidimensional system and in beginning the process of transitioning methods to the new techniques.

This half-day course will benefit analysts, QA and QC managers and researchers, who perform gas chromatography and are seeking the higher resolution and lower detection limits offered by multidimensional GC.  To get the most out of the course, we highly recommended that you have at least one year of experience with GC and at least one previous short course.

1. Transitioning to GC-MS
     * From FID to MS
     * Enhanced qualitative analysis
     * Multiple quantitative analysis options: TIC and SIM
2. Introduction to Multidimensional Chromatography
     * GCxGC Instrumentation
     * Detection Requirements
     * GCxGC-ToFMS
     * Applications and Examples
3. Multidimensional Mass Spectrometry
     * Are three quadrupoles really better than one?
     * Bench-top GC-MS-MS
     * Ion-trap MS-MS
     * Examples and quantitative applications

ABOUT THE INSTRUCTORS Dr. Nicholas H. Snow is Professor and Chair of Chemistry and Biochemistry and Director of the Center for Academic Industry Partnership at Seton Hall University. He teaches advanced undergraduate and graduate courses in analytical chemistry and separation science. He is a subject matter expert for the American Chemical Society’s Sci-Mind training initiative and has taught short courses for over 25 years. He has been recognized twice by the Seton Hall University Board of Regents for outstanding teaching and service to students. He has published 60 refereed articles and chapters on separation science and maintains an active research group with projects involving rapid separations of complex mixtures, multidimensional separations, sampling techniques for chromatography, gas chromatography and gas chromatography/mass spectrometry. He is especially interested in working with industrial partners in solving difficult analytical problems.

Dr. Gregory C. Slack is the Director of Research and Technology Transfer at Clarkson University. In this capacity he oversees the conduct and promotion of sponsored research and technology transfer activities at the University. Dr. Slack received his Ph.D. in Analytical Chemistry from Virginia Polytechnic Institute and State University, Blacksburg, Virginia. He has over 13 years of experience in the pharmaceutical industry serving increasingly responsible research and manufacturing roles at DuPont Merck, DuPont, Bristol-Myers Squibb and Wyeth Pharmaceuticals. Dr. Slack has also had academic experience, serving as adjunct research assistant professor of Chemistry at Clarkson, adjunct professor at SUNY Plattsburgh and instructor of Analytical Chemistry at the University of Massachusetts, Lowell, Continuing Education.